PROTAC IRAK4 degrader-1 - CAS 2360533-90-8

PROTAC IRAK4 degrader-1 (compound I-210) is a Cereblon based PROTAC consisting of the PROTAC IRAK4 ligand-1, the E3 ligase ligand Pomalidomide and the PROTAC linker AM-Imidazole-PA-Boc.

PROTACs, IRAK

NF-κB, Immunology/Inflammation, PROTAC

2360435

0.9976

C44H39F3N12O7

904.85

O=C(NC1=CN(N=C1C(F)(F)F)C2=CC=C(C=C2)C(=O)NCCCN3C=NC(=C3)CNC4=CC=CC=5C(=O)N(C(=O)C45)C6C(=O)NC(=O)CC6)C=7N=C(OC7)C=8C=CN=C(C8)NCC9CC9

-20°C

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PROTAC