PROTAC IRAK4 degrader-8 - CAS 2911615-06-8

PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].

PROTACs, IRAK

PROTAC, Immunology/Inflammation, NF-κB

2911615-06-8

C43H50ClF2N11O5

874.38

C(=O)(N1CCC2(CC1)CCN(C[C@H]3CC[C@@H](CC3)N4C=C(NC(=O)C5=C6N(N=C5)C=CC(=N6)N7[C@@]8(C[C@](C7)(OC8)[H])[H])C(C(F)F)=N4)CC2)C9=CC(=C(Cl)C=C9)N%10C(=O)NC(=O)CC%10

-20°C

Ice Packs

Small Compound