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PROTAC JAK1 degrader 1 - CAS 3052553-20-2

PROTAC JAK1 degrader 1 - CAS 3052553-20-2

MF-0117658-01

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Product Details

  • Bioactivity

    PROTACJAK1 degrader 1 (compound 10c) is a potent and selective PROTAC JAK1 degrader with a DC50 of 214 nM. It also exhibits antitumor activity.

  • Target

    PROTACs

  • Related Pathways

    PROTAC

  • CAS Number

    3052531

  • Molecular Formula

    C44H41N9O6

  • Molecular Weight

    791.85

  • SMILES

    N#CCNC(=O)C=1C=CC(=CC1)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCC(C(=O)NCCCCC#CC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC