PROTAC KRAS G12C degrader-3 - CAS 2768099-51-8

PROTAC KRAS G12C Degrader-3 (Comp 283) serves as a potent degrader of KRAS G12C, utilized in cancer research [1].

Ras

GPCR/G Protein, MAPK

2768040

C63H75ClN14O6

1159.81

C(NCC)(=O)C=1N(C(=NN1)C2=CC(C(C)C)=C(O)C=C2O)C3=CC=C(CN4CCC(C(=O)N5CCN(CC5)[C@H]6C[C@@H](COC7=NC(=C8C(=N7)CN(CC8)C=9C%10=C(C=CC9)C=CC=C%10Cl)N%11C[C@H](CC#N)N(C(C=C)=O)CC%11)N(C)C6)CC4)C=C3

-20°C

Ice Packs

Small Compound