PROTAC Mcl1 degrader-1 - CAS 2163793-38-0

PROTAC Mcl1 degrader-1 is a Cereblon ligand-based targeted chimeric protein degrader (PROTAC), a selective Mcl-1 inhibitor. By hijacking the CRBN ubiquitin ligase to form a ternary complex with the target protein, it induces Mcl-1 ubiquitination. It can be used for cancer research.

PROTACs, Bcl-2 Family

PROTAC, Apoptosis

2163755

0.9874

C45H45BrN6O8S

909.84

O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCCCCNC(=O)CCCCC(=O)NCCN4C(=O)C5=CC=CC=6C(SC7=CC=C(Br)C=C7)=CC=C(C4=O)C56)C3C2=O)CC1

-20°C

Ice Packs

PROTAC