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Molfinity

PROTAC SGK3 degrader-1 - CAS 2381320-35-8

PROTAC SGK3 degrader-1 - CAS 2381320-35-8

SKU:MF-0019879-01

Regular price $39.15 USD
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  • Bioactivity

    PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, inducing degradation of endogenous SGK3. It inhibits GDC0941-induced proliferation of cancer cells. [5017-88-83-4]

  • Target

    PROTACs, SGK

  • Related Pathways

    PROTAC, Metabolism

  • CAS Number

    2381277

  • Molecular Formula

    C57H73FN10O11S2

  • Molecular Weight

    1157.38

  • SMILES

    Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCCCCCN2CCO[C@@H](COc3nc(nc4[nH]ncc34)-c3ccc(NS(=O)(=O)c4cc(C)ccc4F)cc3)C2)C(C)(C)C)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC