PROTAC SMARCA2/4-degrader-35 - CAS 2933253-85-9

PROTAC SMARCA2/4-degrader-35 (Ex.43) is a degrader of SMARCA2/4 with a DC50 value of less than 2.5 nM.

PROTACs

PROTAC

2933159

C56H69N13O6

1020.23

NC1=NC=2N(C=C(N2)C3=C(O)C=CC=C3)C=C1C4=CN(C[C@@H]5C[C@@H](OC6CCN(CC7CCN(CC7)C=8C=C([C@H](C(=O)N9[C@H](C(N[C@@H](C)C%10=CC=C(C=C%10)C%11=CC=NN%11C)=O)C[C@@H](O)C9)C(C)C)ON8)CC6)C5)N=C4

-20°C

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