PROTAC SMARCA2 degrader-23 - CAS 2892523-67-8

PROTAC SMARCA2 degrader-23 (Example 1) is an effective and selective degrader of PROTAC SMARCA2, with a DC50 value of less than 100 nM. It has potential for use in cancer research.

Epigenetic Reader Domain, PROTACs

Chromatin/Epigenetic, PROTAC

2892448

C47H57N9O6S

876.08

OC1=C(C=2C=C3C4(CNC3=NN2)CCN(CC4)C5CN(CCOC=6C=C([C@H](C(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7)C(C)C)ON6)CC5)C=CC=C1

-20°C

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