PROTAC SMARCA2 degrader-31 - CAS 2380274-45-1

PROTAC SMARCA2-degrader-36 (compound 38) is an SMARCA2 degrader that achieves a 99% degradation rate at 100 nM in H929 cells. It possesses antiproliferative activity and is used in cancer research.

PROTACs, Epigenetic Reader Domain

Chromatin/Epigenetic, PROTAC

2380228

C48H65N9O6S

896.15

C([C@@H](NC(CCCCCCCCCC(=O)N1CCN(CC1)C=2C=C(N=NC2N)C3=C(O)C=CC=C3)=O)[C@](C)(C)C)(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4

-20°C

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