PROTAC SOS1 degrader-2 - CAS 2913176-81-3

PROTAC SOS1 degrader-2, a potent degrader of PROTAC SOS1, effectively reduces the expression of pERK and RAS-GTP in a dose-dependent manner. It significantly inhibits tumor growth in vivo [1].

Others, Ras, PROTACs

Others, GPCR/G Protein, MAPK, PROTAC

2913092

C57H76ClFN10O4S

1051.79

C[C@H](NC(=O)[C@@H]1C[C@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCN1CCN(CC1)c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CC2(CNC2)C1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

-20°C

Ice Packs

PROTAC