PROTAC STING Degrader-1 - CAS 2762552-74-7

PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader with a DC50 of 3.2 μM, demonstrating anti-inflammatory activity [1].

PROTACs, STING

Immunology/Inflammation, PROTAC

2762471

C34H33N7O10

699.67

O=[N+](C1=CC=C(O1)C(NC(C=C2)=CC=C2NC(/C=C/C(NCCCCCCNC3=C(C(C(N4C5C(NC(CC5)=O)=O)=O)=CC=C3)C4=O)=O)=O)=O)[O-]

-20°C

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PROTAC