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PROTAC STING Degrader-2 - CAS 3023095-61-3
PROTAC STING Degrader-2 - CAS 3023095-61-3
SKU:MF-0121728-01
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Product Details
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Bioactivity
PROTAC STING Degrader-2 is a protein degrader targeting the Stimulator of interferon genes (STING) with a DC50 of 0.53 μM. It induces STING protein degradation by covalently binding to both the STING protein and an E3 ubiquitin ligase. This compound is useful for studying the role of STING in autoinflammatory and autoimmune diseases.
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Target
PROTACs, STING
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Related Pathways
PROTAC, Immunology/Inflammation
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CAS Number
3023095-61-3
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Molecular Formula
C74H79FN10O15S3
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Molecular Weight
1463.67
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SMILES
C([C@@H](NC(CCC(NCCCNC(=O)C1=CC(S(=O)(=O)N2C=C(C(NCCCCCC(OC3=C(NS(=O)(=O)C4=CC=C(F)C=C4)C=C(NC(=O)C5=CC=C(C=C5)C6=CC=CC=C6)C=C3)=O)=O)C=CC2=O)=CC=C1)=O)=O)[C@@](C)(C)C)(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC