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PROTAC STING Degrader-2 - CAS 3023095-61-3

PROTAC STING Degrader-2 - CAS 3023095-61-3

SKU:MF-0121728-01

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  • Bioactivity

    PROTAC STING Degrader-2 is a protein degrader targeting the Stimulator of interferon genes (STING) with a DC50 of 0.53 μM. It induces STING protein degradation by covalently binding to both the STING protein and an E3 ubiquitin ligase. This compound is useful for studying the role of STING in autoinflammatory and autoimmune diseases.

  • Target

    PROTACs, STING

  • Related Pathways

    PROTAC, Immunology/Inflammation

  • CAS Number

    3023095-61-3

  • Molecular Formula

    C74H79FN10O15S3

  • Molecular Weight

    1463.67

  • SMILES

    C([C@@H](NC(CCC(NCCCNC(=O)C1=CC(S(=O)(=O)N2C=C(C(NCCCCCC(OC3=C(NS(=O)(=O)C4=CC=C(F)C=C4)C=C(NC(=O)C5=CC=C(C=C5)C6=CC=CC=C6)C=C3)=O)=O)C=CC2=O)=CC=C1)=O)=O)[C@@](C)(C)C)(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC