PROTAC α-synuclein degrader 5 - CAS 2781922-42-5

PROTAC α-synuclein degrader 5 is a highly selective (PROTAC) compound targeting and degrading α-synuclein aggregates, with a DC50 value of 7.51 μM and a maximum degradation rate (Dmax) of 89%. It incorporates the probe molecule sery308 and E3 ligase ligands, suitable for neurological disease research [1].

PROTACs

PROTAC

2781875

C39H41N7O10

767.78

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCNC(CNC4=CC(=CC=C4)C=5C=C(NN5)C=6C=C7C(=CC6)OCO7)=O

-20°C

Ice Packs

PROTAC