PROTAC TYK2 degrader-1 - CAS 2770470-20-5

PROTAC TYK2 degrader-1 (CPD-155) functions as a selective degrader of TYK2, demonstrating a degradation maximum (D max) greater than 60%. This compound effectively targets TYK2 for degradation, utilizing a linker to connect the TYK2 ligand with the VHL ligand Thalidomide, each color-coded for identification.

JAK, PROTACs

PROTAC, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Angiogenesis

2770470-20-5

C40H41N13O7

815.84

O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCCNC(=O)C=4C=CC(NC5=CC(NC6=C(OC)C(=CC=C6)C=7N=CN(C)N7)=C(C(NC)=O)N=N5)=NC4

-20°C

Ice Packs

PROTAC