ProTAME - CAS 1362911-19-0

ProTAME is an inhibitor of APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, doxorubicin and etoposide, significantly increase cell death in primary cells and Multiple Myeloma (MM) cell lines, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME.This compound is unstable in powder form and other related salt forms are recommended.

Others, APC/C

Others, Cell Cycle/Checkpoint

1362911-19-0

C34H38N4O12S

726.75

COC(=O)[C@H](CCCN=C(NC(=O)OCOC(=O)Cc1ccccc1)NC(=O)OCOC(=O)Cc1ccccc1)NS(=O)(=O)c1ccc(C)cc1

-20°C

Ice Packs

Small Compound