Protein deglycase DJ-1 against-1 - CAS 724737-74-0

Protein deglycase DJ-1 against-1 (compound 23) is able to penetrate the blood-brain barrier (BBB) and bind to the C106 region of the DJ-1 protein, preventing DJ-1 over-oxidation to enhance cellular resistance to oxidative stress, thereby restoring neuronal cellular observed in a neurotoxin MPTP-induced model of Parkinson's disease (PD) death and motor deficits.

Others, Dopamine Receptor

Others, Neuroscience, GPCR/G Protein

724663

0.9723

C24H23N3O4

417.46

O=C(NC=1C=CC(=CC1)C=2N=C3C(=CC=CN3C2)C)C4=CC(OC)=C(OC)C(OC)=C4

-20°C

Ice Packs

Small Compound