Protoporphyrin IX disodium - CAS 50865-01-5

Protoporphyrin IX disodium, as a radiation sensitizer, enhances the production of ROS and induces DNA damage even under hypoxic conditions. It also acts as a photosensitizer, undergoing direct degradation through photobleaching upon light exposure. This compound accumulates in rat tumor cells following administration of 5-aminolevulinic acid (5-ALA) . When activated with a peak wavelength of 405 nm, Protoporphyrin IX disodium selectively improves basal cell carcinoma. It shows promise in pharmacological research of sonodynamic and photodynamic therapy for cancers such as bladder cancer and nodular basal cell carcinoma.

Endogenous Metabolite

Metabolism

50865-01-5

C34H32N4Na2O4

606.62

O=C(CCC1=C(C)C2=NC1=CC3=C(CCC([O-])=O)C(C)=C(N3)C=C(C(C=C)=C4C)N=C4C=C(C(C=C)=C5C)NC5=C2)[O-].[Na+].[Na+]

-20°C

Ice Packs

Small Compound