Proxyfan - CAS 177708-09-7

Proxyfan (Proxifan) is a high-affinity protean antagonist/agonist of histamine H3 receptors with a full spectrum of pharmacological activity ranging from full agonist to full inverse agonist (antagonist), depending on the competition between constitutively active and resting H3 receptors within a given tissue or brain region.Proxyfan acts as a neutral antagonist in the feeding-associated ventral medial nucleus of the hypothalamus, and as a agonist in the basolateral amygdala of the rat (BLA) .

Histamine Receptor

Neuroscience, Immunology/Inflammation, GPCR/G Protein

177708-09-7

0.9968

C13H16N2O

216.28

N1=CNC(=C1)CCCOCC=2C=CC=CC2

-20°C

Ice Packs

Small Compound