Pruvanserin hydrochloride - CAS 443144-27-2

Pruvanserin hydrochloride (EMD 281014 HCl) is an inverse and selective 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors, respectively. Pruvanserin hydrochloride inhibits GTP-gamma-S accumulation and alleviates tactile allodynia in diabetic rats, making it suitable for studies on Parkinson's disease, insomnia, and schizophrenia.

5-HT Receptor

Neuroscience, GPCR/G Protein

443115

0.996

C22H22ClFN4O

412.89

Cl.N#CC1=CNC2=C1C=CC=C2C(=O)N3CCN(CCC4=CC=C(F)C=C4)CC3

-20°C

Ice Packs

Small Compound