PSB-17365 - CAS 2189700-03-4

PSB-17365 is a potent GPR84 agonist. PSB-17365 exhibits EC50 values vs. GPR84 of 2.5nM in a cAMP accumulation assay, and 100nM in a β-arrestin 2 recruitment assay. No direct binding affinities are provided. PSB-17365 is selective for GPR84 compared to other free fatty acid receptors (FFAR1 and FFAR4) . GPR84, a Gi protein-coupled receptor that is activated by medium-chain (hydroxy) fatty acids, appears to play an important role in inflammation, immunity, and cancer.

Others

Others

2189700-03-4

C12H12BrN3O2

310.15

N(CCC1=CC=C(Br)C=C1)C2=CC(=O)NC(=O)N2

-20°C

Ice Packs

Small Compound