PSF-IN-2 - CAS 185418-37-5

PSF-IN-2 (Compound (C) -30) is a PSF inhibitor with an IC50 value of 0.005 pM. It exhibits anticancer properties, inhibiting the proliferation of 22Rv1 cells with an IC50 value of 0.5 μM. PSF-IN-2 activates the p53 signaling pathway by disrupting PSF-RNA binding, inducing expression of related genes, promoting apoptosis, and inhibiting the cell cycle. This compound is applicable in cancer research.

MDM-2/p53, Apoptosis

Apoptosis

185376

C18H16O5

312.317

O=C1OC=2C(OC)=C(OC)C=CC2C(=C1)C=3C=CC(OC)=CC3

-20°C

Ice Packs

Small Compound