PSI-353661 - CAS 1231747-08-2

PSI-353661 (GS-558093), a purine nucleotide NS5B polymerase inhibitor, is effective against HCV infection, displaying EC90 values of 8 nM and 11 nM for wild-type and S282T resistant HCV replicons, respectively. It is capable of generating high concentrations of the active triphosphate form in primary human hepatocytes [1] [3].

Others, HCV Protease

Others, Microbiology/Virology, Proteases/Proteasome

1231747-08-2

C24H32FN6O8P

582.52

COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](COP(=O)(N[C@@H](C)C(=O)OC(C)C)Oc2ccccc2)[C@@H](O)[C@@]1(C)F

-20°C

Ice Packs

Small Compound