PSI-7409 tetrasodium - CAS 1621884-22-7

PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively.

HCV Protease, Others

Proteases/Proteasome, Microbiology/Virology, Others

1621855

C10H16FN2Na4O14P3

592.117

[Na].[Na].[Na].[Na].[H][C@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@@]1(C)F)n1ccc(=O)[nH]c1=O

-20°C

Ice Packs

Small Compound