PSMA-trillium - CAS 3036415-37-6

PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator) . It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC) .

PSMA

Immunology/Inflammation

3036372

C106H156IN17O34S

2371.44

C(COCCOCCOCCC(N[C@@H](CCCCNC(NC1=CC=C(CCOC=2C=C(CN3CCOCCOCCN(CC=4N=C(C(O)=O)C=CC4)CCOCCOCC3)N=C(C(O)=O)C2)C=C1)=S)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCCCNC(CCCC5=CC=C(I)C=C5)=O)C(O)=O)=O)=O)=O)N6C=C(N=N6)C7=CC(NC(NCCCC[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)C(O)=O)=O)=CC=C7

-20°C

Ice Packs

Small Compound