PT-S58 - CAS 1356497-92-1

PT-S58 is a PPAR β/δ full antagonist, and a derivative of GSK0660. PT-S58 has a three-fold higher affinity for the receptor than GSK0660 and is a potent inhibitor of agonist-induced target gene expression. PT-S58 are effective on PPRE-independent functions of PPARβ/δ. Unlike GSK0660, PT-S58 blocks the recruitment co-repressor molecules such as SMRT.

Others, PPAR

Metabolism, Others, DNA Damage/DNA Repair

1356404

C17H22N2O5S2

398.5

S(NC1=C(OC)C=C(NC(C)(C)C)C=C1)(=O)(=O)C2=C(C(OC)=O)SC=C2

-20°C

Ice Packs

Small Compound