PT-ttpy - CAS 727721-37-1

Pt-ttpy is a metallo-organic compound and an effective G-quadruplex ligand that efficiently induces significant telomere-associated DNA damage in cancer cells by inhibiting telomerase and/or telomere function. It also causes various chromatin abnormalities during mitosis, such as chromatin bridges, ultrafine bridges (UFB), and double-stranded breaks (DSB) .

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

727721-37-1

C22H17Cl2N3Pt

589.38

-20°C

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Inhibitors & Agonists