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PTC-700 - CAS 2476726-76-6
PTC-700 - CAS 2476726-76-6
SKU:MF-0118015-01
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Product Details
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Bioactivity
PTC-700 is an effective splicing modulator of microtubule-associated protein tau (MAPT) . It reduces 4R MAPT in P301L and S305N neurons with EC50 values of 1.3 to 1.8 nM and 0.5 to 2.6 nM, respectively.
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Target
Microtubule Associated
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Related Pathways
Cytoskeletal Signaling
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CAS Number
2476644
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Molecular Formula
C15H17ClN4S2
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Molecular Weight
352.91
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SMILES
N(CC1=NC=CS1)C2=C3C(C(C)=C(C[C@H](C)N)S3)=NC(Cl)=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound