PtdIns- (4,5) -P2 (1,2-dipalmitoyl) sodium - CAS 1628353-01-4

Phosphatidylinositol- (4,5) -P2 (1,2-dipalmitoyl), a synthetic analog of natural phosphatidylinositol (PtdIns) with C16:0 fatty acids at the sn-1 and sn-2 positions, maintains the inositol and diacylglycerol (DAG) stereochemistry of its natural counterpart. Although phosphatidylinositol phosphates constitute a minor fraction of total membrane phospholipids, they are pivotal in initiating and propagating cellular signals. This compound mirrors the activity of the natural phosphatidylinositol produced by PtdIns-4-phosphate 5-kinase's action on PtdIns- (4) -P1. Its hydrolysis by phosphoinositide (PI) -specific phospholipase C yields inositol triphosphate (IP3) and DAG, crucial secondary messengers in a complex signal transduction pathway.

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1628353-01-4

C41H78O19P3?3Na

1036.9

O(P(=O)(O)O)[C@H]1[C@H](OP(=O)(O)O)[C@@H](O)[C@@H](O)[C@@H](OP(OC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(=O)O)[C@@H]1O.[Na]

-20°C

Ice Packs

Small Compound