Purine riboside-5'-O-triphosphate sodium - CAS 35892-95-6

Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 μM and 28 μM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 μM.

DNA/RNA Synthesis, Nucleoside Antimetabolite/Analog, CaMK

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Neuroscience

35791

C10H11N4Na4O13P3

580.09

O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)N2C3=NC=NC=C3N=C2.[Na+].[Na+].[Na+].[Na+]

-20°C

Ice Packs

Small Compound