Puromycin aminonucleoside - CAS 58-60-6

Puromycin aminonucleoside (NSC 3056) is an aminonucleoside antibiotic and a purine analog of puromycin. It can reversibly inhibit dipeptidyl peptidase and cytosolic alanine aminopeptidase, increase podocyte permeability by regulating ZO-1 in an oxidative stress-dependent manner, induce apoptosis, and promote the secretion of migrasomes. It is commonly used to induce nephrotic syndrome models in research.

Apoptosis, Proteasome, Antibiotic, Antibacterial, Aminopeptidase

Apoptosis, Proteases/Proteasome, Ubiquitination, Metabolism, Microbiology/Virology

-8

0.9997

C12H18N6O3

294.31

CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](N)[C@H]1O

-20°C

Ice Packs

Small Compound