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Puxitatug samrotecan drug-linker - CAS 3025787-81-6
Puxitatug samrotecan drug-linker - CAS 3025787-81-6
SKU:MF-0121764-01
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Product Details
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Bioactivity
Puxitatug samrotecan drug-linker (AZD8205 drug-linker), comprising a degradable ADC linker and the topoisomerase I inhibitor Exatecan, is utilized in the ADC (drug-linker conjugate for ADC) targeting the anti-B7-H4 antibody.
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Target
Drug-Linker Conjugates for ADC, Topoisomerase
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Related Pathways
Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
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CAS Number
3025787-81-6
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Molecular Formula
C60H84N8O20S
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Molecular Weight
1269.42
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SMILES
O=C1N2C(C=3C(=C4C=5C(N3)=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(=O)C(SC[C@@H](C(O)=O)N)CC6=O)=O)=O)C(C)C)=O)C)=O)C5CCC4)C2)=CC7=C1COC(=O)[C@@]7(CC)O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound