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PV-1019 - CAS 1093793-05-5
PV-1019 - CAS 1093793-05-5
SKU:MF-0146702-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
PV-1019 (NSC 744039) is a potent and selective inhibitor of Chk2 with an IC50 of 24 nM, effectively inhibiting Topotecan-induced Chk2 autophosphorylation and suppressing IR-induced apoptosis [1].
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Target
Chk, Others
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Related Pathways
Cell Cycle/Checkpoint, Others
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CAS Number
1093793-05-5
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Molecular Formula
C18H17N7O3
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Molecular Weight
379.37
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SMILES
N(=O)(=O)C1=C2C(C=C(C(NC3=CC=C(C(=NNC(=N)N)C)C=C3)=O)N2)=CC=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound