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Molfinity

PV-1019 - CAS 1093793-05-5

PV-1019 - CAS 1093793-05-5

SKU:MF-0146702-01

Regular price $1,383.80 USD
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  • Bioactivity

    PV-1019 (NSC 744039) is a potent and selective inhibitor of Chk2 with an IC50 of 24 nM, effectively inhibiting Topotecan-induced Chk2 autophosphorylation and suppressing IR-induced apoptosis [1].

  • Target

    Chk, Others

  • Related Pathways

    Cell Cycle/Checkpoint, Others

  • CAS Number

    1093793-05-5

  • Molecular Formula

    C18H17N7O3

  • Molecular Weight

    379.37

  • SMILES

    N(=O)(=O)C1=C2C(C=C(C(NC3=CC=C(C(=NNC(=N)N)C)C=C3)=O)N2)=CC=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound