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Molfinity

PVZB1194 - CAS 1141768-04-8

PVZB1194 - CAS 1141768-04-8

MF-0156570-01

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Product Details

  • Bioactivity

    PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 allosteric pocket and demonstrates ATP-competitive activity [1].

  • Target

    Kinesin

  • Related Pathways

    Cytoskeletal Signaling

  • CAS Number

    1141768-04-8

  • Molecular Formula

    C13H9F4NO2S

  • Molecular Weight

    319.28

  • SMILES

    O=S(=O)(N)C1=CC=C(C=C1)C=2C=CC(=C(F)C2)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound