PWT-33597 free base - CAS 1246203-32-6

PWT-33597 (VDC-597) free base is a dual inhibitor of PI3Kα and mTOR that effectively obstructs downstream signaling pathways of PI3K and mTOR. This compound induces apoptosis in tumor cells and inhibits tumor growth. PWT-33597 free base demonstrates antitumor activity and can be used in research related to renal cell carcinoma and other tumors.

PI3K, Apoptosis, mTOR

Apoptosis, PI3K/Akt/mTOR signaling

1246165

C26H30F2N8O4S

588.63

O=S(=O)(NC=1C=CC(=CC1)C=2N=C(N=C(N2)N3CCOCC3)N4C(=NC=5C(OC)=CC=CC54)C(F)F)CCN(C)C

-20°C

Ice Packs

Small Compound