PWT33597 mesylate - CAS 1246203-36-0

PWT33597, also known as VDC-597, is an orally bioavailable dual inhibitor of phosphatidylinositide 3-kinase (PI3K) alpha and mammalian target of rapamycin (mTOR) kinase with potential antineoplastic activity. PI3K alpha/mTOR dual inhibitor PWT33597 selectively inhibits both PI3K alpha kinase and mTOR kinase, which may result in tumor cell apoptosis and growth inhibition in PI3K/mTOR-overexpressing tumor cells.

Others, PI3K, Apoptosis, mTOR

Others, Apoptosis, PI3K/Akt/mTOR signaling

1246167

C27H34F2N8O7S2

684.7348

CS(O)(=O)=O.COc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)-c1ccc(NS(=O)(=O)CCN(C)C)cc1)N1CCOCC1

-20°C

Ice Packs

Small Compound