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Molfinity

PX20606 - CAS 1268245-19-7

PX20606 - CAS 1268245-19-7

MF-0148074-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    PX20606 is an orally active farnesoid X receptor (FXR) agonist, demonstrating EC50 values of 220 nM (mFXR) and 50 nM (hFXR) in Gal4-FXR assays. It induces the expression of the tumor suppressor gene NDRG2 and inhibits tumor growth and metastasis in a mouse HCC model. Additionally, PX20606 exhibits hepatoprotective properties.

  • Target

    FXR

  • Related Pathways

    Metabolism

  • CAS Number

    1268245-19-7

  • Molecular Formula

    C29H22Cl3NO4

  • Molecular Weight

    554.85

  • SMILES

    O=C(O)C1=CC=C(C=C1)C2CC2C3=CC=C(OCC=4C(=NOC4C5CC5)C=6C(Cl)=CC=CC6Cl)C=C3Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound