PXS-6302 - CAS 2584947-54-4

PXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate the skin, reduces collagen deposition and cross-linking, and significantly improves scar appearance without reducing tissue strength. PXS-6302 also has potentially broader applications in other fibrotic diseases.

Others, Monoamine Oxidase

Neuroscience, Others

2584889

C10H10F3NO2S

265.25

S(C(/C(=C/CN)/F)(F)F)(=O)(=O)C1=CC=CC=C1

-20°C

Ice Packs

Small Compound