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PY-PAP - CAS 2765218-57-1
PY-PAP - CAS 2765218-57-1
SKU:MF-0118492-01
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Product Details
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Bioactivity
PY-PAP is a photoactivatable affinity probe, derived from PY-60. It retains its cellular function of activating YAP transcription. In 293A cells, PY-PAP can label cathepsin D (CTSD) and annexin A2 (ANXA2) through UV crosslinking and click reactions. PY-PAP played a crucial role in identifying ANXA2 as a specific target of PY-60.
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Target
Annexin A, YAP
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Related Pathways
GPCR/G Protein, Stem Cells
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CAS Number
2765160
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Molecular Formula
C25H30N6O3
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Molecular Weight
462.54
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SMILES
O=C(NCCCN1CCN(C(=O)CCC2(N=N2)CCC#C)CC1)C3=NOC(=C3)C=4C=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Dye-Reagents