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Molfinity

Pyr10 - CAS 1315323-00-2

Pyr10 - CAS 1315323-00-2

MF-0015704-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor that distinguishes between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1) /Orai1 channels. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells (IC50: 0.72 μM) and has an IC50 of 13.08 μM for store-operated Ca2+ entry in BRL-2H3 cells.

  • Target

    TRP/TRPV Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1315323-00-2

  • Purity

    0.997

  • Molecular Formula

    C18H13F6N3O2S

  • Molecular Weight

    449.37

  • SMILES

    Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound