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Pyrazole N-Desmethyl sildenafil - CAS 139755-95-6
Pyrazole N-Desmethyl sildenafil - CAS 139755-95-6
SKU:MF-0114291-01
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Product Details
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Bioactivity
Pyrazole N-Desmethyl sildenafil (Compound 10) is an analogue of Sildenafil. At a concentration of 100 μM, it inhibits the activity of the Trypanosoma brucei phosphodiesterase TbrPDEB1 by 16%.
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Target
Parasite, PDE
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Related Pathways
Microbiology/Virology, Metabolism
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CAS Number
139654
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Molecular Formula
C21H28N6O4S
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Molecular Weight
460.55
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SMILES
CCCc1[nH]nc2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound