Pyridinium bisretinoid A2E TFA - CAS 1821308-73-9

Pyridinium bisretinoid A2E (A2E) TFA, a fluorophore derived from retinal pigment epithelium (RPE) lipofuscin, initiates blue-light-induced apoptosis, mediates autophagy, and generates reactive oxygen species. This compound is instrumental in researching retinal degenerative diseases [1] [2].

Autophagy, Apoptosis, Reactive Oxygen Species, ROS

NF-κB, Immunology/Inflammation, Apoptosis, Metabolism, Autophagy

1821226

C44H58F3NO3

705.93

C(C([O-])=O)(F)(F)F.C(CO)[N+]=1C(/C=C(/C=C/C=C(/C=C/C=2C(C)(C)CCCC2C)\C)\C)=CC(/C=C/C=C(/C=C/C=3C(C)(C)CCCC3C)\C)=CC1

-20°C

Ice Packs

Dye-Reagents