Pyridostatin hydrochloride - CAS 1781882-65-2

Pyridostatin (RR82) hydrochloride, a G-quadruplex DNA stabilizing agent (Kd = 490 nM), induces replication- and transcription-dependent DNA damage, promoting growth arrest in human cancer cells. It specifically targets the proto-oncogene Src, leading to reduced SRC protein levels and decreased SRC-dependent cellular motility in human breast cancer cells.

Others, DNA/RNA Synthesis

Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair

1781815

C31H37Cl5N8O5

778.94

Cl.Cl.Cl.Cl.Cl.NCCOc1cc(nc(c1)C(=O)Nc1cc(OCCN)c2ccccc2n1)C(=O)Nc1cc(OCCN)c2ccccc2n1

-20°C

Ice Packs

Small Compound