Molfinity

Pyrotinib dimaleate - CAS 1397922-61-0

SKU:MF-0014359-01

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Product Details

Bioactivity
Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor with IC50 values of 13 and 38 nM, respectively, for the treatment of HER2-positive breast cancer.
Target
HER, EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
CAS Number
1397861
Purity
0.9952
Molecular Formula
C40H39ClN6O11
Molecular Weight
815.22
SMILES
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\[C@H]1CCCN1C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound