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Pyruvate Carboxylase-IN-1 - CAS 70205-50-4
Pyruvate Carboxylase-IN-1 - CAS 70205-50-4
SKU:MF-0142132-01
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$1,927.85 USD
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$1,927.85 USD
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Product Details
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Bioactivity
Pyruvate Carboxylase-IN-1 (compound 37), a natural analog of erianin, is a potent inhibitor of pyruvate carboxylase (PC), with inhibitory concentrations (IC50) of 0.204 μM and 0.104 μM in cell lysate-based and cell-based PC activity assays, respectively. This compound effectively inhibits PC enzymatic activity, contributing to its anticancer effects in human hepatocellular carcinoma (HCC) [1].
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Target
Others, Mitochondrial Metabolism
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Related Pathways
Metabolism, Others
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CAS Number
70151
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Molecular Formula
C15H14O3
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Molecular Weight
242.27
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SMILES
OC1=C2C=3C(CCC2=CC(OC)=C1)=CC=CC3O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound