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Molfinity

Quarfloxin - CAS 865311-47-3

Quarfloxin - CAS 865311-47-3

MF-0014284-01

$60.83 USD
$60.83 USD
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Product Details

  • Bioactivity

    Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA template.

  • Target

    DNA/RNA Synthesis

  • Related Pathways

    DNA Damage/DNA Repair, Cell Cycle/Checkpoint

  • CAS Number

    865261

  • Purity

    0.9977

  • Molecular Formula

    C35H33FN6O3

  • Molecular Weight

    604.67

  • SMILES

    CN1CCC[C@H]1CCNC(=O)c1cn2c3cc4ccccc4cc3oc3c(N4CCC(C4)c4cnccn4)c(F)cc(c23)c1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound