Quetiapine - CAS 111974-69-7

Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the α1 adrenoreceptor and α2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor.

Histamine Receptor, Dopamine Receptor, 5-HT Receptor, AChR, Adrenergic Receptor

GPCR/G Protein, Neuroscience, Immunology/Inflammation

111898

>99.99%

C21H25N3O2S

383.51

OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12

-20°C

Ice Packs

Small Compound