Quin-2 (potassium salt) - CAS 73630-23-6

Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium) . It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH. High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells. Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation/emission maxima for quin-2 are 339 and 492 nm, respectively.

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73601

C26H23K4N3O10

693.87

[K].COc1cc(N(CC(O)=O)CC(O)=O)c2nc(COc3cc(C)ccc3N(CC(O)=O)CC(O)=O)ccc2c1

-20°C

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