Quipazine - CAS 4774-24-7

Quipazine, a 5-HT (serotonin) agonist, demonstrates affinity for the 5-HT3R receptor in rats with a Ki value of 1.4 nM, effectively displacing GR65630. It exhibits antiviral activity against SARS-CoV-2, achieving an EC50 of 31.64 μM. Additionally, Quipazine acts as a 5-HT3R agonist in peripheral models, indicating its potential for neurological disease research.

Others, SARS-CoV, 5-HT Receptor

GPCR/G Protein, Microbiology/Virology, Neuroscience, Others

4743

C13H15N3

213.28

C1CN(CCN1)c1ccc2ccccc2n1

-20°C

Ice Packs

Small Compound