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QX-314 bromide - CAS 24003-58-5
QX-314 bromide - CAS 24003-58-5
SKU:MF-0019612-01
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Product Details
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Bioactivity
QX-314 bromide is a membrane-impermeable sodium channel blocker that inhibits TRPV1 and NaV1.8 expression, causing sensory-selective blockade of TRPV1 channels. It exhibits anti-inflammatory effects and may be used in studies of gastroesophageal reflux disease (GERD) .
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Target
Sodium Channel, TRP/TRPV Channel
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Related Pathways
Membrane transporter/Ion channel
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CAS Number
23940
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Purity
0.9905
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Molecular Formula
C16H27BrN2O
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Molecular Weight
343.3
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SMILES
[Br-].O=C(NC=1C(=CC=CC1C)C)C[N+](CC)(CC)CC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound