(R) -4-Amino-3-hydroxybutyric Acid - CAS 7013-07-2

(R) -4-Amino-3-hydroxybutyric acid, also known as (R) -GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.

Others, GABA Receptor

Membrane transporter/Ion channel, Others, Neuroscience

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C4H9NO3

119.12

NC[C@H](O)CC(O)=O

-20°C

Ice Packs

Small Compound